fbpx
  1. Home
  2. »
  3. Pandemic Pulse
  4. »
  5. Patient-Led Researchers Publish Comprehensive Study on Long COVID

Patient-Led Researchers Publish Comprehensive Study on Long COVID

Facebook
Twitter
LinkedIn
Print
On January 13, 2023, a major study authored by Hannah E. Davis, Lisa McCorkell, Julia Moore Vogel, and Eric J. Topol was published in Nature Reviews Microbiology. This study, titled "Long COVID: major findings, mechanisms and recommendations," provides a comprehensive overview of long COVID and the current understanding of the associated pathophysiology.

On January 13, 2023, a major study authored by Hannah E. Davis, Lisa McCorkell, Julia Moore Vogel, and Eric J. Topol was published in Nature Reviews Microbiology. This study, titled “Long COVID: major findings, mechanisms and recommendations,” provides a comprehensive overview of long COVID and the current understanding of the associated pathophysiology. The study outlines the various symptoms and organ impacts of long COVID and identifies risk factors, as well as similarities with other viralonset illnesses. Additionally, the study examines the current diagnostic and treatment options, and the role of vaccinations. The authors note that while there has been significant progress in understanding long COVID, future research must be prioritized to further the understanding of this chronic illness and develop better treatment options.

The study authors call for a comprehensive long COVID research agenda that builds upon existing knowledge from ME/CFS, dysautonomia and other viralonset conditions, including but not limited to brain and brainstem inflammation, neuroimmunology, metabolic profiling, mitochondrial fragmentation, antiviral and metabolic phenotypes, hypoperfusion/cerebral blood flow, nanoneedle diagnostic testing, overlaps with connective tissue disorders, autoimmunity and autoantibodies, viral/microbial persistence, intracranial hypertension, hypermobility, craniocervical obstructions, altered T and B cells, metabolomics and proteomics, elevated blood lactate level, herpesvirus reactivations, immune changes in the early versus late post-viral years, and changes to the gut microbiota.

Additionally, the study authors call for prioritizing robust clinical trials for potential treatments, as patients currently have few treatment options. Research on long COVID be representative of the populations who had COVID19 and are developing long COVID at high rates. Additionally, the study authors recommend that medical schools improve their education on pandemics, viruses and infectioninitiated illnesses such as long COVID and ME/CFS. In addition to providing education on long COVID to the biomedical community, the study authors call emphasize the need for a public communications campaign that informs the public about the risks and outcomes of long COVID. Finally, the study authors advocate for policies and funding that will sustain long COVID research and enable people with long COVID to receive adequate care and support.

The study authors are affiliated with the Patient-Led Research Collaborative, which is a group of long COVID patients who are also researchers. The mission of the Patient-Led Research Collaborative is to facilitate patient-led and patient-involved research into Long COVID and associated conditions while following rigorous research methodology, and to advocate for policies that enable patients, particularly the most marginalized, to access care and live with dignity.

Pandemic Policy in the 2023 Federal Budget

On Dec. 29, 2022, President Biden signed the Consolidated Appropriations Act of 2023 into law, funding the federal government through September 2023. The final budget, spanning 1653 pages, enacts many changes to public policy, some of which are related to the coronavirus pandemic.

How Do I Apply for Social Security Disability Benefits?

If you meet the eligibility requirements for Social Security Disability Insurance (SSDI) or Supplemental Security Income (SSI) programs, you may be able to receive disability benefits, even if you are not covered by a private or employer-sponsored disability insurance plan.

Can My Employer Terminate Me After I Request Workplace Accommodations?

“I’m experiencing debilitating long-term symptoms of COVID-19, including vertigo and cognitive impairment. I notified my employer about my disability and requested accommodations to help me perform my job duties. Shortly afterward, I was terminated from my job. Were my rights violated?”