- The Race to Retain Healthcare Workers: A Systematic Review on Factors that Impact Retention of Nurses and Physicians in Hospitals: This systematic review examines the prevalence of nurses and physicians leaving their positions in European hospitals and the factors influencing job retention among them.
- Social Illness Before and After the COVID-19 Pandemic: A Regional Study: This study aimed to evaluate the trend of broad social problems, such as a diagnosis by the emergency department, in the post-pandemic phase of COVID-19.
- Post-traumatic stress disorder among COVID-19-affected high-risk cardiac patients: This study found that 31.4% of hospitalized patients with cardiac problems and suspected COVID-19 had PTSD during waves 2-5 of the pandemic. No age or gender differences were found.
- The Thresholds of Caprini Score Associated With Increased Risk of Venous Thromboembolism Across Different Specialties: A Systematic Review: This study aims to determine the specific thresholds of the Caprini Risk Score (CRS) that are associated with an increased incidence of Venous Thromboembolism (VTE) across different specialties, with the goal of identifying the highest level of risk.
- Is virtual nutritional counseling efficacious for cancer patients during the COVID-19 pandemic: This study examined the effects of virtual nutritional counseling (VNC) on the nutritional status of cancer patients during the Covid-19 pandemic. The dietitian evaluated the patients via video call and sent individual nutrition plans and recommendations via email. The Patient-Generated Subjective Global Assessment (PG-SGA) was used to assess the outcomes.
- Glycan masking of a non-neutralising epitope enhances neutralising antibodies targeting the RBD of SARS-CoV-2 and its variants: The development of the first generation of COVID-19 vaccines has saved millions of lives, but new variants of SARS-CoV-2 have evolved and may escape from natural infection or vaccine-induced immunity provided by the original SARS-CoV-2 spike protein.
- Predictors of impaired functioning among long COVID patients: This study aimed to explore the factors that predict long-term symptoms of COVID-19. Data was collected from patients with Long COVID-19 at two time points, with a mean duration of 21.7 weeks between them. At time point 2, participants also completed the Hospital Anxiety and Depression Scale (HADS) to assess their mental health. Results showed that initial symptom severity, fatigue, and anxiety were predictive of long-term symptoms.
- Identification of phytochemical compounds of Fagopyrum dibotrys and their targets by metabolomics, network pharmacology and molecular docking studies: Traditional Chinese medicine has been found to be effective in treating acute lung injury (ALI) and COVID-19, but there is still a lack of drugs available for these diseases.
- Application of the PHENotype SIMulator for rapid identification of potential candidates in effective COVID-19 drug repurposing: The PHENotype SIMulator is a systems biology tool that leverages existing knowledge on host-immune response to SARS-CoV-2 infection to identify potential drug candidates for COVID-19. This tool can help accelerate the process of finding effective treatments for the virus.
- Gross Hematuria following SARS-CoV-2 Vaccination: We report the self-limited occurrence of gross hematuria in two elderly men on a combination of aspirin and another antiplatelet or anticoagulant following their second COVID-19 vaccine dose. Clinicians and front-line healthcare workers should be aware of this potential side effect.
- The role of the mass vaccination programme in combating the COVID-19 pandemic: An LSTM-based analysis of COVID-19 confirmed cases: This study aims to predict the future number of COVID-19 confirmed cases in the top ten countries with the highest number of vaccinations in the world using a Deep Learning model. The results of this study will help inform public health policy decisions and provide insight into the effectiveness of mass vaccination programmes.
- Application of the PHENotype SIMulator for rapid identification of potential candidates in effective COVID-19 drug repurposing: The PHENotype SIMulator is a systems biology tool that uses existing knowledge on host-immune response to SARS-CoV-2 infection to identify potential drug candidates for COVID-19. It leverages data from multiple sources to predict the efficacy of existing drugs, offering significant promise for repurposing existing drugs to treat the virus.
- Post-exertional malaise among people with long COVID compared to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): We conducted a survey to compare post-exertional malaise (PEM), the hallmark symptom of ME/CFS, in people with Long COVID and those with ME/CFS. Our results showed that people with Long COVID experienced PEM at a similar rate to those with ME/CFS.
- My experience with ME/CFS and implications: A personal narrative: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic, debilitating health condition characterized by overwhelming fatigue and post-exertional malaise. It can have a significant impact on an individual’s life, and the long-term effects of COVID-19 have brought increased attention to this condition.
- Predictors of impaired functioning among long COVID patients: This study aimed to explore which acute factors predict longer-term symptoms of COVID-19. Data from patients with Long COVID-19 was collected at two time points, with a mean duration of 21.7 weeks between them. At the second time point, participants completed the Hospital Anxiety and Depression Scale (HADS) to assess their symptoms. An exploratory factor analysis was conducted to identify any potential predictors of long-term symptoms.
- Post-COVID-19 sequelae in lungs: retrospective computed tomography analysis in selected tertiary care hospitals of Mangalore: This study aims to document and assess the proportion of residual changes in the lungs post-COVID-19 infection, as well as to look for evidence and the proportion of fibrosis post-COVID-19 infection on high-resolution computed tomography (HRCT).
- Emergence of Post COVID-19 Vaccine Autoimmune Diseases: A Single Center Study: SARS CoV-2 vaccine trials were completed rapidly in 2020 due to the urgency of the pandemic. Minor side effects such as injection site pain and fever have been reported, as well as a rare adverse event known as post-vaccination thrombotic thrombocytopenia (PVT). PVT is a serious condition that can lead to blood clots and low platelet levels, and requires immediate medical attention.
- The mast cell exosome-fibroblast connection: A novel pro-fibrotic pathway: We report that mast cell exosomes are a source of pro-fibrotic substances and can generate excess collagen in primary human lung fibroblasts. We used primary human lung fibroblasts to demonstrate the uptake of mast cell exosomes and show that these exosomes induce the production of excess collagen.
- Case report: Immune profiling links neutrophil and plasmablast dysregulation to microvascular damage in post-COVID-19 Multisystem Inflammatory Syndrome in Adults (MIS-A): Deep phenotyping of an individual with MIS-A revealed immunologic responses that were distinct from those of healthy, convalescent, and acute COVID-19 patients. These findings suggest that MIS-A is a distinct post-infectious syndrome with its own immunologic profile.
Daily News Pulse for March 13, 2023
Summary: Princeton students have seen an overall improvement in course satisfaction since the start of the COVID-19 pandemic. In Japan, many people are still wearing masks despite the government’s easing of guidelines.
