- COVID-19 And Contributions from Animal-based Research
- Metabolic control during the first two years of the COVID-19 pandemic in pediatric patients with type 1 diabetes: results from the German DPV initiative: This study aims to assess the effects of the SARS-CoV2 pandemic on metabolic control in youth with type 1 diabetes (T1D) in Germany. Data from 33,372 pediatric T1D patients from the Diabetes Prospective Follow-up (DPV) registry were analyzed over eight time periods between March 15, 2020 and December 31, 2021. Results showed that metabolic control worsened during the pandemic, with higher HbA1c levels and lower insulin dose per kg body weight.
- The effects of Covid-19 mRNA vaccine on adolescence gynecological well-being: This study investigates the effects of the Covid-19 mRNA vaccine on adolescent girls’ menstrual health, and found that while it may cause some menstrual abnormalities, it does not affect ovarian reserve as estimated by AMH.
- Pediatrics, Students, Allied Health and COVID-19: This issue of JORH for 2023 considers research related to pediatrics, students, allied health professions, and COVID-19. It also provides a reminder about the call for papers regarding “Religion, Spirituality, Suicide, and its Prevention” and a new call for papers on “Spiritual Care for People with Parkinson’s Disease and their Caregivers”.
- The importance of high quality real-life social interactions during the COVID-19 pandemic: This study investigated the effect of the quality of real-life and online social interactions on mood, and explored whether this association was mediated by the amygdala. Results showed that higher quality social interactions were associated with better mood, and that this association was partially mediated by the amygdala.
- Vaccine effectiveness and duration of protection of COVID-19 mRNA vaccines against Delta and Omicron BA.1 symptomatic and severe COVID-19 outcomes in adults aged 50 years and over in France: This study estimated the effectiveness of 2-dose primary and booster COVID-19 mRNA vaccine regimens against Delta and Omicron BA.1 symptomatic infection and severe outcomes in French residents aged 50 and over.
- The effects of Covid-19 mRNA vaccine on adolescence gynecological well-being: This study investigates the potential influence of the Covid-19 mRNA vaccine on adolescent girls’ menstrual cycles and ovarian reserve, and found that while menstrual cycles may be affected, the ovarian reserve estimated by AMH is not compromised.
- Molecular-evaluated and explainable drug repurposing for COVID-19 using ensemble knowledge graph embedding: We propose a new drug repurposing approach for COVID-19 based on knowledge graph embeddings. Our approach learns “ensemble embeddings” of entities and relations in a COVID-19 centric KG, in order to get a better latent representation of the data and identify potential drugs that may be effective against the virus.
- Cutaneous exanthema revealing Multisystem-Inflammatory Syndrome in adults (MIS-A) in the course of SARS-CoV-2 infection
- Nurses perspective of apheresis in SARS-CoV-2 infected patients: The COVID-19 pandemic has had a huge impact on the entire global population, causing fear of infection and making it difficult to organize apheresis units worldwide.
- Down-regulation of MALAT1 is a hallmark of tissue and peripheral proliferative T cells in COVID-19: We studied expression of long non-coding RNAs (lncRNAs) in COVID-19 T cell transcriptomes and found that MALAT1 was the most highly transcribed lncRNA, with Th1 cells demonstrating the lowest and CD8+ resident memory cells the highest expression.
- Assessment of microbiota in the gut and upper respiratory tract associated with SARS-CoV-2 infection: We conducted a large-scale study to evaluate the effect of SARS-CoV-2 infection on human microbiota in patients with COVID-19. Our findings suggest that SARS-CoV-2 infection can significantly alter the composition of the gut and oral pharynx microbiome, which may have implications for host-viral interactions and COVID-19 pathogenesis.
- COVID 19 convalescent plasma: Is there still a place for CCP: This review discusses the use of convalescent plasma, which is collected from recovered patients and transfused to infectious patients, as a treatment for various infectious diseases, including SARS-CoV-2. It summarizes relevant studies on collection and transfusion of convalescent plasma and its potential benefits.
- Nursing home crowding and its association with outbreak-associated respiratory infection in Ontario, Canada before the COVID-19 pandemic (2014-19): a retrospective cohort study: This study aimed to measure the association between crowding in nursing homes and outbreak-associated respiratory infection incidence and related mortality before the COVID-19 pandemic. A retrospective cohort study of nursing homes in Ontario, Canada was conducted to assess this association. Results showed that crowding was associated with higher incidence of respiratory infection outbreaks and higher mortality rates.
- Durability and breadth of neutralisation following multiple antigen exposures to SARS-CoV-2 infection and/or COVID-19 vaccination: This study analyzed the long-term neutralizing antibody responses to an ancestral SARS-CoV-2 isolate and cross-neutralization to delta and omicron isolates in individuals previously infected with SARS-CoV-2, in order to inform immunization strategies.
- Quality of life and ability to work of patients with Post-COVID syndrome in relation to the number of existing symptoms and the duration since infection up to 12 months: a cross-sectional study: This study aims to analyze the change in health-related quality of life (HRQoL) of patients 18-65 years old who have been infected with SARS-CoV-2 virus, depending on the duration since infection and the accumulation of symptoms. Additionally, other possible influencing factors will be analyzed.
- Risk factors associated with limited functional status among out-of-hospital patients 30 days and one year after a diagnosis of COVID-19: a cohort study: This study examined the long-term health consequences of COVID-19 in non-hospitalized adults in Londrina, Brazil, at 30 days and one year after diagnosis. Variables were analyzed to determine which predict limitations in functional status.
Daily News Pulse for March 13, 2023
Summary: Princeton students have seen an overall improvement in course satisfaction since the start of the COVID-19 pandemic. In Japan, many people are still wearing masks despite the government’s easing of guidelines.