- Progressive Observation of Covid-19 Vaccination Effects on Skin-Cellular Structures by Use of Intelligent Laser Speckle Classification (ILSC) Technique: Researchers have developed a multi-disciplinary approach using AI, laser-optics, and imaging methods to observe the subtle effects of vaccines on human metabolisms in an emergency period, such as the recent pandemic. This technique can make progressive observations on Covid-19 and help make better and speedy evolutionary health assessments.
- Relationship between intensive care surge capacity and hospital factors: an extensive experience: This study evaluates the relationship between Intensive Care Unit Surge Capacity (ICU-SC) and hospital-related variables such as bed occupancy, emergency department admissions, ward admission from ED, and elective surgery procedures in a large hospital network during the COVID-19 pandemic. Pearson’s partial correlation analysis was used to analyze the data and results showed that ICU-SC was significantly correlated with all four variables.
- [Surgical emergencies during the COVID-19 pandemic]: This study investigated the effects of the COVID-19 pandemic on surgical emergencies at the Rostock University Medical Center, comparing the results to the years before. The case numbers of surgical emergencies were analyzed and compared to previous years, in order to determine the impact of the pandemic.
- Risk factors of SARS-CoV-2 infection and complications from COVID-19 in lung cancer patients: This study aimed to identify characteristics of lung cancer patients that predict an increased risk of death or serious SARS-CoV-2 infection. A retrospective cohort study was conducted on patients with lung cancer diagnosed between January 1, 2020 and June 30, 2020. Results showed that older age, male gender, and comorbidities were associated with an increased risk of death or serious SARS-CoV-2 infection.
- A peek behind the curtain in the diagnosis and management of COVID‑19‑Associated Mucormycosis (CAM): COVID-19 patients with uncontrolled diabetes, metabolic acidosis, prolonged neutropenia, increased ferritin levels, hypoxia, and prolonged hospitalization are at higher risk of developing CAM (Coronavirus disease 2019-associated mucormycosis), which has a high mortality rate.
- Global loss of cellular m6A RNA methylation following infection with different SARS-CoV-2 variants: Research into host-viral interactions during SARS-CoV-2 infection may help to guide the design of novel antiviral therapeutics. N6-methyladenosine modification (m6A) is one of the most abundant cellular RNA modifications and regulates key processes in RNA metabolism during a stress response. Changes in the expression of genes related to m6A readers and writers have been observed post-infection with different SARS-CoV-2 variants, suggesting that m6A plays an important role in the virus’s pathogenesis.
- Poor air passenger knowledge of COVID-19 symptoms and behaviour undermines strategies aimed at preventing the import of SARS-CoV-2 into the UK: This study of UK adults (n = 2103) quantified knowledge of COVID-19 symptoms, perceived health risk of contracting COVID-19, likelihood of returning to the UK with COVID-19 symptoms, likelihood to obey self-quarantining guidelines, how safe air travellers felt when flying during the pandemic (n = 305), and perceptions of air travel safety during the pandemic.
- Oligonucleotide usage in coronavirus genomes mimics that in exon regions in host genomes: Researchers studied the adaptation mechanisms of a zoonotic virus to host cells by comparing the frequency of oligonucleotides in the genome of the virus between different host cells.
- Development of Acute Transverse Myelitis following COVID-19 Infection: A Review on the Potential Pathways: Acute transverse myelitis (ATM) is a rare neurological disorder in adults that may be caused by SARS-CoV-2. Possible pathways include direct invasion of the spinal cord, cytokine storm, or an autoimmune response.
- Dual mechanism: Epigenetic inhibitor apabetalone reduces SARS-CoV-2 Delta and Omicron variant spike binding and attenuates SARS-CoV-2 RNA induced inflammation: The SARS-CoV-2 virus binds to ACE2 receptors on host cells with its spike protein, and variants of concern have mutations that increase the binding affinity. Viral RNAs released into host cells trigger IFN-I responses for viral clearance, but overreactive IFN-I responses can lead to pro-inflammatory signals.
- Clinical validation of a contactless respiration rate monitor: This study evaluates the accuracy of a contactless device, Sleepiz, for measuring respiratory rate at home. Results show that Sleepiz is a reliable and accurate tool for monitoring respiratory rate remotely.
- Covid-19: Vaccination reduces severity and duration of long covid, study finds
- Differences in perception of online anesthesiology between Thai medical students and teachers during the COVID-19 pandemic: This study aims to compare students’ and teachers’ perceptions of online anesthesiology learning by conducting a prospective descriptive study using a cross-sectional survey.
- Headache as a COVID-19 onset symptom or Post-COVID symptom according to the SARS-CoV-2 Variant: This article examines the prevalence of headaches as a symptom of COVID-19 and its association with different SARS-CoV-2 variants. It discusses the differences in the prevalence of headache as an onset symptom and in post-COVID headache among different variants, as well as the prognostic implications and immune response associated with headaches.
- SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice: SARS-CoV-2 Spike protein has been found to reach the CNS, and brain infusion of this protein in mice has been shown to have a late impact on cognitive function. The underlying mechanisms of this cognitive dysfunction are not yet fully understood.
- Female reproductive health during the COVID-19 pandemic: latest evidence and understanding: This review examines the impact of the COVID-19 pandemic on female reproductive health. It looks at the literature that adds to our understanding of how SARS-CoV-2 affects the reproductive system and how it can be managed.
- Sexual behaviour, STI and HIV testing and testing need among gay, bisexual and other men who have sex with men recruited for online surveys pre/post-COVID-19 restrictions in the UK: This study examined sexual behavior, STI and HIV testing, and associated factors among GBMSM in the UK after COVID-19 restrictions ended. Data was collected from 1039 GBMSM via social media and Grindr in November-December 2021, and compared with pre-pandemic estimates. Results showed increased HIV testing, but decreased condom use and STI testing. Factors associated with increased HIV testing included younger age, higher education, and higher income.
- COVID-19 long-term sequelae: Omicron versus Alpha and Delta variants: This study examined the correlation between three SARS-CoV-2 variants (Alpha, Delta, and Omicron) and the risk of developing long COVID, post-COVID-19 syndrome, and viral persistence in 325 hospitalized COVID-19 patients.
Daily News Pulse for March 13, 2023
Summary: Princeton students have seen an overall improvement in course satisfaction since the start of the COVID-19 pandemic. In Japan, many people are still wearing masks despite the government’s easing of guidelines.