- A single-item measure of self-rated mental health and psychological distress. In what situations can a single-item measure be useful: This study examined the association between self-rated mental health (SRMH) and psychological distress (PD) at multiple periods in order to assess the potential of SRMH as a screening tool. Staff working at a designated COVID-19 hospital in Sydney, Australia completed the SRMH and Kessler Psychological Distress Scale (K10) survey during March to May 2020.
- Exploring the challenges of and solutions to sharing personal genomic data for use in healthcare: This study examines how providing educational information affects individuals’ willingness to consent to sharing their genomic data. It is motivated by the increased concern for privacy due to the COVID-19 pandemic and GDPR legislation in the EU.
- Nirmatrelvir-ritonavir Therapy and COVID-19 Vaccination Improve Clinical Outcomes of SARS-CoV-2 Omicron Variant Infection: We retrospectively analyzed the clinical data of 762 adult patients with confirmed Omicron BA2.2 variant infection, and used propensity score matching and nearest-neighbor matching to evaluate the effect of Nirmatrelvir-ritonavir therapy and COVID-19 vaccination on clinical outcomes.
- The predictive role of fatigue and neuropsychological components on functional outcomes in COVID-19 after a multidisciplinary rehabilitation program: This study aimed to investigate the effects of altered cognitive functioning and increased mental fatigue, both reported after COVID-19, on rehabilitation treatment outcomes. A retrospective pre-post intervention cohort study was conducted to evaluate cognitive functioning and levels of fatigue, depression and anxiety symptoms in individuals who had been admitted to a rehabilitation program. Results showed that cognitive functioning improved significantly after rehabilitation, while levels of fatigue, depression and anxiety decreased. These findings suggest that rehabilitation programs can be beneficial for individuals with COVID-19 related cognitive impairments and mental fatigue.
- Persistent SARS-CoV-2 infection in patients seemingly recovered from COVID-19: Post-mortem analyses of 27 patients who had recovered from COVID-19 but had worsened in their clinical conditions despite repeated negative tests for SARS-CoV-2 RNA showed that the virus was still present in the lungs and other organs, indicating that the virus can persist even after recovery.
- Diagnosing post-COVID-19 condition (long COVID) in adults
- Treating common and potentially modifiable symptoms of post-COVID-19 condition (long COVID) in adults
- Is the post-COVID-19 syndrome a severe impairment of acetylcholine-orchestrated neuromodulation that responds to nicotine administration: Post-COVID-19 syndrome is caused by SARS-CoV-2 related spike glycoprotein (SGP) attaching to nicotinic acetylcholine receptors (nAChRs), which can lead to weakness, memory lapses, pain, dyspnea and other physical complaints.
Summary: Governor John Carney has tested positive for COVID-19 and is working from home. The 7-day average of new cases in Delaware is 135, with 158 hospitalizations. A new study has found that 71% of people with long COVID required medical treatment or were unable to work for six months or more. The FDA has withdrawn emergency use authorization for the COVID-19 antibody drug Evusheld due to its ineffectiveness against the Omicron variants now dominating the US.