- Outcomes of the same-day discharge following mastectomy before, during and after COVID-19 pandemic: This study found that the rates of outpatient mastectomy before, during, and after the COVID-19 pandemic were similar and that same-day discharge is safe.
- Changes in social lives and loneliness during COVID-19 among older adults: a closer look at the sociodemographic differences: This study looked at how different aspects of social connection (structural, functional, and quality) are associated with loneliness during the COVID-19 pandemic. It also looked at how these associations vary by sociodemographic factors.
- RNA Editing: Expanding the Potential of RNA Therapeutics: RNA therapeutics have had a tremendous impact on medicine, recently exemplified by the rapid development and deployment of mRNA vaccines to combat the COVID-19 pandemic. In addition, RNA-targeting drugs have been developed for diseases with significant unmet medical needs through selective mRNA knockdown or modulation of pre-mRNA splicing. Recently, RNA editing, particularly antisense RNA-guided Adenosine Deaminase Acting on RNA (ADAR) based programmable A-to-I editing, has emerged as a powerful tool for the treatment of genetic diseases.
- Challenges and future opportunities to unlock the critical supply chain of personal and protective equipment (PPE) encompassing decontamination and reuse under emergency use authorization conditions d: SARS-CoV-2 is a virus that causes the disease COVID-19. It was declared a global health emergency by the World Health Organization in early 2020. There is still much to learn about the virus and how to best manage it, but response plans are being developed.
- Endothelial function, arterial stiffness and heart rate variability of patients with cardiovascular diseases hospitalized due to COVID-19: COVID-19 may cause problems with the vascular system, the heart, and the autonomic nervous system. It may also cause a systemic inflammatory response. People with pre-existing cardiovascular diseases may be at higher risk.
- Are PID-5 personality traits and self-harm attitudes related? A study on a young adult sample pre-post COVID-19 pandemic: There is a stronger link between maladaptive personality traits and non-suicidal self-injury in people who have experienced the COVID-19 pandemic.
- Perioperative Challenges in the Management of Rhino-Orbital Cerebral Mucormycosis: An Observational Study from a Tertiary Care Hospital: This study looked at patients with rhino orbital cerebral mucormycosis (ROCM), which is a disease associated with COVID-19. The study found that Amphotericin B and surgical debridement are the most effective treatment modalities.
- Outcomes of the same-day discharge following mastectomy before, during and after COVID-19 pandemic: This study found that the rates of outpatient mastectomy increased during the COVID-19 pandemic, which may suggest that same-day discharge is safe.
- COVID ‘variant soup’ is making winter surges hard to predict
- Large interfacial relocation in RBD-ACE2 complex may explain fast-spreading property of Omicron: The Omicron variant of SARS-CoV-2 emerged in South Africa in late 2021. This variant has a large number of mutations, and is regarded as the fastest-spreading Covid variant.
- The influence of new SARS-CoV-2 variant Omicron (B.1.1.529) on vaccine efficacy, its correlation to Delta variants: A computational approach: The new COVID variant in Botswana has many mutations and is concerning to scientists. Our findings provide insights into the structural modification caused by the mutations and look into the effects on interaction with the hosts’ neutralizing antibodies.

Daily News Pulse for April 05, 2023
Summary: The domestic box office is close to reaching pre-pandemic levels, with mid-budget films helping to bring moviegoers back. Research has found that diabetes is a major factor in the severity of COVID-19 cases. The US government is planning to authorize booster doses of the vaccine for high-risk populations.